Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetCaspase-3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340527((S)-1-(4-(2-(2-fluoroethoxy)ethoxy)benzyl)-5-(2-(p...)
Affinity DataIC50:  27.9nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340527((S)-1-(4-(2-(2-fluoroethoxy)ethoxy)benzyl)-5-(2-(p...)
Affinity DataIC50:  28.9nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-6(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340527((S)-1-(4-(2-(2-fluoroethoxy)ethoxy)benzyl)-5-(2-(p...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of caspase 6 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340527((S)-1-(4-(2-(2-fluoroethoxy)ethoxy)benzyl)-5-(2-(p...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of caspase 1 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340527((S)-1-(4-(2-(2-fluoroethoxy)ethoxy)benzyl)-5-(2-(p...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of caspase 8 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50340527((S)-1-(4-(2-(2-fluoroethoxy)ethoxy)benzyl)-5-(2-(p...)
Affinity DataEC50:  2.15E+3nMAssay Description:Inhibition of staurosporine induced activation of caspase 3 activation in human Hela cells assessed as hydrolysis of Z-DEVD-R110 substrate by micropl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed