Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetCaspase-3(Homo sapiens (Human))
Washington University

LigandPNGBDBM10336((S)-1-(2-Fluoro-pyridin-4-yl-methyl)-5-(2-phenoxym...)
Affinity DataIC50:  21.3nMpH: 7.4 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University

LigandPNGBDBM10336((S)-1-(2-Fluoro-pyridin-4-yl-methyl)-5-(2-phenoxym...)
Affinity DataIC50:  21.4nMAssay Description:Inhibition of caspase3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University

LigandPNGBDBM10336((S)-1-(2-Fluoro-pyridin-4-yl-methyl)-5-(2-phenoxym...)
Affinity DataIC50:  58nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-6(Homo sapiens (Human))
Washington University

LigandPNGBDBM10336((S)-1-(2-Fluoro-pyridin-4-yl-methyl)-5-(2-phenoxym...)
Affinity DataIC50: >5.00E+3nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Washington University

LigandPNGBDBM10336((S)-1-(2-Fluoro-pyridin-4-yl-methyl)-5-(2-phenoxym...)
Affinity DataIC50: >5.00E+4nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Washington University

LigandPNGBDBM10336((S)-1-(2-Fluoro-pyridin-4-yl-methyl)-5-(2-phenoxym...)
Affinity DataIC50: >5.00E+4nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed