Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM50342703(CHEMBL1771104 | rac-4-(3-(2-(3-(1-(5-chloropyrimid...)Copy SMILESCopy InChI

Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM50342703(CHEMBL1771104 | rac-4-(3-(2-(3-(1-(5-chloropyrimid...)Copy SMILESCopy InChI

Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Merck

Curated by ChEMBL

LigandBDBM50342703(CHEMBL1771104 | rac-4-(3-(2-(3-(1-(5-chloropyrimid...)Copy SMILESCopy InChI

Affinity DataEC50:  0.800nMAssay Description:Agonist activity at mouse GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...More data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI