Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Axovant Sciences

US Patent

LigandBDBM410150(US10370370, Compound (R)-42)Copy SMILESCopy InChI

Affinity DataKi:  260nMAssay Description:h-5HT3: In brief, Chinese Hamster Ovary (CHO) cells stably expressing human 5-HT3 serotonin receptors, grown to confluence in 175 cm2 flasks. Followi...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Axovant Sciences

US Patent

LigandBDBM410150(US10370370, Compound (R)-42)Copy SMILESCopy InChI

Affinity DataKi:  1.55E+3nMAssay Description:α7 nAChR: The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affin...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI