Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Aurigene Discovery Technologies

Curated by ChEMBL

LigandBDBM50585939(CHEMBL5094993)Copy SMILESCopy InChI

Affinity DataIC50:  100nMAssay Description:Inhibition of full-length human MEK1 by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 3A4(Homo sapiens (Human))
Aurigene Discovery Technologies

Curated by ChEMBL

LigandBDBM50585939(CHEMBL5094993)Copy SMILESCopy InChI

Affinity DataIC50: <500nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI