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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat))
Siena Biotech
Curated by
ChEMBL
Ligand
BDBM50319673
(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
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Affinity Data
Ki: 44nM
Assay Description:
Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 4
(Homo sapiens (Human))
Siena Biotech
Curated by
ChEMBL
Ligand
BDBM50319673
(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
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Affinity Data
Ki: 6.00E+3nM
Assay Description:
Binding affinity to 5HT4 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Siena Biotech
Curated by
ChEMBL
Ligand
BDBM50319673
(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
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Affinity Data
IC50: 1.30E+3nM
Assay Description:
Binding affinity to human ERG expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Alpha-2B adrenergic receptor
(Homo sapiens (Human))
Siena Biotech
Curated by
ChEMBL
Ligand
BDBM50319673
(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
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Affinity Data
IC50: 7.50E+3nM
Assay Description:
Binding affinity to adrenergic alpha2B receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Homo sapiens (Human))
Siena Biotech
Curated by
ChEMBL
Ligand
BDBM50319673
(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
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Copy InChI
Affinity Data
IC50: >3.00E+4nM
Assay Description:
Agonist activity at alpha4beta2 nAChR
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
Siena Biotech
Curated by
ChEMBL
Ligand
BDBM50319673
(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
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Affinity Data
IC50: >3.00E+4nM
Assay Description:
Agonist activity at human 5HT3A receptor expressed in HEK293 cells by FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-2A adrenergic receptor
(Homo sapiens (Human))
Siena Biotech
Curated by
ChEMBL
Ligand
BDBM50319673
(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
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Copy InChI
Affinity Data
IC50: 3.50E+4nM
Assay Description:
Binding affinity to adrenergic alpha2A receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat))
Siena Biotech
Curated by
ChEMBL
Ligand
BDBM50319673
(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 490nM
Assay Description:
Agonist activity at rat rat alpha7 nAChR expressed in rat GH4C1 cells by whole cell patch-clamp electrophysiology
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat))
Siena Biotech
Curated by
ChEMBL
Ligand
BDBM50319673
(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 70nM
Assay Description:
Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI