Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 18 hits in this display   

Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

LigandBDBM50458553(CHEMBL4218672)Copy SMILESCopy InChI

Affinity DataKi:  52nMAssay Description:Displacement of [3H]LSD from human 5-HT7 receptor expressed in HEK cell membranes after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
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Ligand InfoPC cidPC sid

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Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

LigandBDBM50458553(CHEMBL4218672)Copy SMILESCopy InChI

Affinity DataKi:  53nMAssay Description:Human gene recombinant 5-HT7 receptor expressed in Chinese hamster ovary (CHO) cells was used. [3H]LSD 1 nM, the 5-HT7 receptor membrane (15 μg/...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
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Ligand InfoPC cidPC sid

In DepthDetails US Patent
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Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

LigandBDBM50458553(CHEMBL4218672)Copy SMILESCopy InChI

Affinity DataKi:  53nMAssay Description:Displacement of [3H]LSD from human 5-HT7 receptor expressed in HEK cell membranes after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

LigandBDBM50458553(CHEMBL4218672)Copy SMILESCopy InChI

Affinity DataKi:  471nMAssay Description:Displacement of [3H]LSD from human 5-HT2A receptor expressed in HEK cell membranes after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

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Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

LigandBDBM50458553(CHEMBL4218672)Copy SMILESCopy InChI

Affinity DataKi:  505nMAssay Description:Displacement of [3H]LSD from human 5-HT2B receptor expressed in HEK cell membranes after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

LigandBDBM50458553(CHEMBL4218672)Copy SMILESCopy InChI

Affinity DataKi:  703nMAssay Description:Displacement of [3H]LSD from human 5-HT3 receptor expressed in HEK cell membranes after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
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Ligand InfoPC cidPC sid

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Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

LigandBDBM50458553(CHEMBL4218672)Copy SMILESCopy InChI

Affinity DataKi:  785nMAssay Description:Displacement of [3H]LSD from human 5-HT2C receptor expressed in HEK cell membranes after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
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Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

LigandBDBM50458553(CHEMBL4218672)Copy SMILESCopy InChI

Affinity DataKi:  1.23E+3nMAssay Description:Displacement of [3H]LSD from human 5-HT5A receptor expressed in HEK cell membranes after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

LigandBDBM50458553(CHEMBL4218672)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]LSD from human 5-HT1B receptor expressed in HEK cell membranes after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

LigandBDBM50458553(CHEMBL4218672)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]LSD from human 5-HT1A receptor expressed in HEK cell membranes after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

LigandBDBM50458553(CHEMBL4218672)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]LSD from human 5-HT1D receptor expressed in HEK cell membranes after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

LigandBDBM50458553(CHEMBL4218672)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]LSD from human 5-HT4 receptor expressed in HEK cell membranes after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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Target5-hydroxytryptamine receptor 1E(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

LigandBDBM50458553(CHEMBL4218672)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]LSD from human 5-HT1E receptor expressed in HEK cell membranes after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

LigandBDBM50458553(CHEMBL4218672)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in HEK cell membranes after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

LigandBDBM50458553(CHEMBL4218672)Copy SMILESCopy InChI

Affinity DataIC50:  2.46E+3nMAssay Description:Antagonist activity at human 5-HT7 receptor expressed in HEK293 cells assessed as inhibition of Gs protein-mediated cAMP accumulation by luminescence...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

LigandBDBM50458553(CHEMBL4218672)Copy SMILESCopy InChI

Affinity DataIC50:  2.46E+3nMAssay Description:Antagonist activity at human 5-HT7 receptor expressed in HEK293 cells assessed as inhibition of Gs protein-mediated cAMP accumulation by luminescence...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

LigandBDBM50458553(CHEMBL4218672)Copy SMILESCopy InChI

Affinity DataEC50:  135nMAssay Description:Agonist activity at tTA containing TCS cleavage site-fused 5-HT7 receptor (unknown origin) expressed in tTA-dependent luciferase reporter/TEV-fused b...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

LigandBDBM50458553(CHEMBL4218672)Copy SMILESCopy InChI

Affinity DataEC50:  135nMAssay Description:Agonist activity at tTA containing TCS cleavage site-fused 5-HT7 receptor (unknown origin) expressed in tTA-dependent luciferase reporter/TEV-fused b...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI