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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetHistone deacetylase 4(Homo sapiens (Human))
Bharati Vidyapeeth'S College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50593367(CHEMBL5183909)
Affinity DataIC50:  800nMAssay Description:Inhibition of recombinant human N-terminal His6-SUMO-tagged C-terminal SII-tagged HDAC4 expressed in Escherichia coli (BL21) DE3 pLysS cells using Bo...More data for this Ligand-Target Pair
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TargetHistone deacetylase 7(Homo sapiens (Human))
Bharati Vidyapeeth'S College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50593367(CHEMBL5183909)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HDAC7 (518 to end residues) expressed in baculovirus infected sf9 insect cells using BocLys(tri...More data for this Ligand-Target Pair
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TargetHistone deacetylase 1(Homo sapiens (Human))
Bharati Vidyapeeth'S College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50593367(CHEMBL5183909)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of recombinant human C-terminal His6-FLAG-tagged HDAC1 (1 to end residues) expressed in sf9 insect cells using Boc-Lys(acetyl)-AMC as subs...More data for this Ligand-Target Pair
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TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Bharati Vidyapeeth'S College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50593367(CHEMBL5183909)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of C-terminal His-tagged recombinant human HDAC3 (1 to 428 residues)/N-terminal GST-tagged recombinant human NCoR2 (395 to 489 residues) c...More data for this Ligand-Target Pair
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TargetHistone deacetylase 6(Homo sapiens (Human))
Bharati Vidyapeeth'S College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50593367(CHEMBL5183909)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(acetyl)-AMC as substrate incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Bharati Vidyapeeth'S College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50593367(CHEMBL5183909)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of recombinant human HDAC2 Boc-Lys(acetyl)-AMC as substrate incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Bharati Vidyapeeth'S College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50593367(CHEMBL5183909)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of recombinant human N-terminal His6-SUMO-tagged C-terminal SII-tagged HDAC8 expressed in Escherichia coli (BL21) DE3 pLysS cells using Bo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed