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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 10 hits in this display   

TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50390404(CHEMBL2070936)
Affinity DataIC50:  15nMAssay Description:Inhibition of human recombinant cathepsin-k using Z-Phe-Arg-AMC as substrate preincubated for 15 mins measured after 1 hr by QFRET assayMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50390404(CHEMBL2070936)
Affinity DataIC50:  15nMAssay Description:Inhibition of cathepsin-kMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50390404(CHEMBL2070936)
Affinity DataIC50:  15.8nMAssay Description:Inhibition of human recombinant cathepsin K using Z-Phe-Arg-AMC as substrate preincubated for 30 mins measured after 1 hr by quenched fluorescent res...More data for this Ligand-Target Pair
TargetCathepsin B(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50390404(CHEMBL2070936)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant cathepsin B using Z-Arg-Arg-AMC as substrate preincubated for 30 mins measured after 1 hr by quenched fluorescent res...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50390404(CHEMBL2070936)
Affinity DataIC50:  1.09E+3nMAssay Description:Inhibition of human recombinant cathepsin-B using Z-Arg-Arg-AMC as substrate preincubated for 15 mins measured after 1 hr by QFRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50390404(CHEMBL2070936)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of human recombinant cathepsin S using Z-Val-Val-Arg-AMC as substrate preincubated for 30 mins measured after 1 hr by quenched fluorescent...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50390404(CHEMBL2070936)
Affinity DataIC50:  1.31E+3nMAssay Description:Inhibition of human recombinant cathepsin-S using Z-Val-Val-Arg-AMC as substrate preincubated for 15 mins measured after 1 hr by QFRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50390404(CHEMBL2070936)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant cathepsin-L using Z-Phe-Arg-AMC as substrate preincubated for 15 mins measured after 1 hr by QFRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50390404(CHEMBL2070936)
Affinity DataIC50:  3.16E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50390404(CHEMBL2070936)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant cathepsin L using Z-Phe-Arg-AMC as substrate preincubated for 30 mins measured after 1 hr by quenched fluorescent res...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed