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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat))
Janssen Pharmaceutica
US Patent
Ligand
BDBM60551
(BDBM50448656 | US9102669, 54)
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Affinity Data
IC50: 31nM
T: 2°C
Assay Description:
The SCD1 enzymatic assay was done in a volume of 50 μL using 10 μg of RLM (prepared as described above) in a 96-well polypropylene plate (e...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
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Target
Stearoyl-CoA desaturase
(Homo sapiens (Human))
Janssen Research And Development
Curated by
ChEMBL
Ligand
BDBM60551
(BDBM50448656 | US9102669, 54)
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Affinity Data
IC50: 54nM
Assay Description:
Inhibition of SCD1 in human A431 cells assessed as [13C]-palmitic acid conversion to [13C]-palmitoleic acid after 4 hrs by LC/MS analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat))
Janssen Pharmaceutica
US Patent
Ligand
BDBM60551
(BDBM50448656 | US9102669, 54)
Copy SMILES
Copy InChI
Affinity Data
IC50: 90nM
Assay Description:
Inhibition of SCD1 in Sprague-Dawley rat liver microsomes using stearoyl-[9,10-3H]-CoA as substrate
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat))
Janssen Pharmaceutica
US Patent
Ligand
BDBM60551
(BDBM50448656 | US9102669, 54)
Copy SMILES
Copy InChI
Affinity Data
IC50: 90nM
T: 2°C
Assay Description:
The SCD1 enzymatic assay was done in a volume of 50 μL using 10 μg of RLM (prepared as described above) in a 96-well polypropylene plate (e...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI