Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hits in this display   

TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Amgen

Curated by ChEMBL

LigandBDBM50264761(3-(2-chloro-3-fluorophenyl)-5-(1-(piperidin-4-yl)-...)Copy SMILESCopy InChI

Affinity DataEC50:  230nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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