Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 25 hits in this display
BDBM406663(US10336752, Compound 1 | US10336752, Compound 2 | ...)
BDBM406663(US10336752, Compound 1 | US10336752, Compound 2 | ...)
BDBM406663(US10336752, Compound 1 | US10336752, Compound 2 | ...)
BDBM406663(US10336752, Compound 1 | US10336752, Compound 2 | ...)
IC50: 72.6nMAssay Description:Compounds were serially diluted in DMSO then further diluted in 1x kinase buffer: 5 uL of buffer diluted compound was added into wells first, then 10...More data for this Ligand-Target Pair
BDBM406663(US10336752, Compound 1 | US10336752, Compound 2 | ...)
IC50: 72.6nMAssay Description:Compounds were serially diluted in DMSO then further diluted in 1× kinase buffer: 5 uL of buffer diluted compound was added into wells first, then 10...More data for this Ligand-Target Pair
BDBM406663(US10336752, Compound 1 | US10336752, Compound 2 | ...)
IC50: 78.5nMAssay Description:Compounds were serially diluted in DMSO then further diluted in 1× kinase buffer: 5 uL of buffer diluted compound was added into wells first, then 10...More data for this Ligand-Target Pair
BDBM406663(US10336752, Compound 1 | US10336752, Compound 2 | ...)
IC50: 78.5nMAssay Description:Compounds were serially diluted in DMSO then further diluted in 1x kinase buffer: 5 uL of buffer diluted compound was added into wells first, then 10...More data for this Ligand-Target Pair
BDBM406663(US10336752, Compound 1 | US10336752, Compound 2 | ...)
IC50: 85.3nMAssay Description:Compounds were serially diluted in DMSO then further diluted in 1x kinase buffer: 5 uL of buffer diluted compound was added into wells first, then 10...More data for this Ligand-Target Pair
BDBM406663(US10336752, Compound 1 | US10336752, Compound 2 | ...)
IC50: 85.3nMAssay Description:Compounds were serially diluted in DMSO then further diluted in 1× kinase buffer: 5 uL of buffer diluted compound was added into wells first, then 10...More data for this Ligand-Target Pair
BDBM406663(US10336752, Compound 1 | US10336752, Compound 2 | ...)
IC50: 93.2nMAssay Description:Compounds were serially diluted in DMSO then further diluted in 1× kinase buffer: 5 uL of buffer diluted compound was added into wells first, then 10...More data for this Ligand-Target Pair
BDBM406663(US10336752, Compound 1 | US10336752, Compound 2 | ...)
IC50: 93.2nMAssay Description:Compounds were serially diluted in DMSO then further diluted in 1x kinase buffer: 5 uL of buffer diluted compound was added into wells first, then 10...More data for this Ligand-Target Pair
BDBM406663(US10336752, Compound 1 | US10336752, Compound 2 | ...)
IC50: 110nMAssay Description:Inhibition of TYK2 in human PBMC assessed as inhibition of IL-12-stimulated phosphorylation of STAT4 measured by immunoblotting methodMore data for this Ligand-Target Pair
BDBM406663(US10336752, Compound 1 | US10336752, Compound 2 | ...)
BDBM406663(US10336752, Compound 1 | US10336752, Compound 2 | ...)
BDBM406663(US10336752, Compound 1 | US10336752, Compound 2 | ...)
BDBM406663(US10336752, Compound 1 | US10336752, Compound 2 | ...)
BDBM406663(US10336752, Compound 1 | US10336752, Compound 2 | ...)
BDBM406663(US10336752, Compound 1 | US10336752, Compound 2 | ...)
BDBM406663(US10336752, Compound 1 | US10336752, Compound 2 | ...)
BDBM406663(US10336752, Compound 1 | US10336752, Compound 2 | ...)
BDBM406663(US10336752, Compound 1 | US10336752, Compound 2 | ...)
BDBM406663(US10336752, Compound 1 | US10336752, Compound 2 | ...)
BDBM406663(US10336752, Compound 1 | US10336752, Compound 2 | ...)
BDBM406663(US10336752, Compound 1 | US10336752, Compound 2 | ...)
BDBM406663(US10336752, Compound 1 | US10336752, Compound 2 | ...)