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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19701((2S)-3-cyclohexyl-2-{[5-(3-fluorophenyl)furan-2-yl...)
Affinity DataKi:  34nM ΔG°:  -44.3kJ/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19701((2S)-3-cyclohexyl-2-{[5-(3-fluorophenyl)furan-2-yl...)
Affinity DataKi:  4.08E+3nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Gnf

LigandPNGBDBM19701((2S)-3-cyclohexyl-2-{[5-(3-fluorophenyl)furan-2-yl...)
Affinity DataKi:  1.17E+4nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed