Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 26 hits in this display   

Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

LigandBDBM50579346(CHEMBL4867565)Copy SMILESCopy InChI

Affinity DataKi:  0.930nMAssay Description:Binding affinity to 5HT3 receptor (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
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Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

LigandBDBM50579346(CHEMBL4867565)Copy SMILESCopy InChI

Affinity DataKi:  3nMAssay Description:Displacement of [3H]-LSD from human 5HT6 receptor expressed in HEK293 cell membranes measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
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TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

LigandBDBM50579346(CHEMBL4867565)Copy SMILESCopy InChI

Affinity DataKi:  110nMAssay Description:Binding affinity to human adrenergic alpha 2A receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
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TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

LigandBDBM50579346(CHEMBL4867565)Copy SMILESCopy InChI

Affinity DataKi:  170nMAssay Description:Binding affinity to human adrenergic beta1 receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
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Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

LigandBDBM50579346(CHEMBL4867565)Copy SMILESCopy InChI

Affinity DataKi:  170nMAssay Description:Binding affinity to human 5-HT2B receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
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TargetD(3) dopamine receptor(Homo sapiens)
Jagiellonian University Medical College

Curated by ChEMBL

LigandBDBM50579346(CHEMBL4867565)Copy SMILESCopy InChI

Affinity DataKi:  210nMAssay Description:Binding affinity to human dopamine D3 receptorMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
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TargetHistamine H1 receptor(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

LigandBDBM50579346(CHEMBL4867565)Copy SMILESCopy InChI

Affinity DataKi:  220nMAssay Description:Binding affinity to human histamine H1 receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
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Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

LigandBDBM50579346(CHEMBL4867565)Copy SMILESCopy InChI

Affinity DataKi:  437nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cell membranes measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

LigandBDBM50579346(CHEMBL4867565)Copy SMILESCopy InChI

Affinity DataKi:  830nMAssay Description:Binding affinity to human 5-HT2C receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
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Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

LigandBDBM50579346(CHEMBL4867565)Copy SMILESCopy InChI

Affinity DataKi:  890nMAssay Description:Binding affinity to human 5-HT1B receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
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TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

LigandBDBM50579346(CHEMBL4867565)Copy SMILESCopy InChI

Affinity DataKi:  940nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
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TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

LigandBDBM50579346(CHEMBL4867565)Copy SMILESCopy InChI

Affinity DataKi:  1.09E+3nMAssay Description:Binding affinity to human DATMore data for this Ligand-Target Pair

Target InfoNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
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TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

LigandBDBM50579346(CHEMBL4867565)Copy SMILESCopy InChI

Affinity DataKi:  1.24E+3nMAssay Description:Binding affinity to human NETMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
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TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

LigandBDBM50579346(CHEMBL4867565)Copy SMILESCopy InChI

Affinity DataKi:  1.94E+3nMAssay Description:Binding affinity to human M1 receptorMore data for this Ligand-Target Pair

Target InfoReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
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Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

LigandBDBM50579346(CHEMBL4867565)Copy SMILESCopy InChI

Affinity DataKi:  2.87E+3nMAssay Description:Binding affinity to human 5-HT5A receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
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TargetMu-type opioid receptor(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

LigandBDBM50579346(CHEMBL4867565)Copy SMILESCopy InChI

Affinity DataKi:  2.88E+3nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

LigandBDBM50579346(CHEMBL4867565)Copy SMILESCopy InChI

Affinity DataKi:  3.00E+3nMAssay Description:Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cell membranes measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

LigandBDBM50579346(CHEMBL4867565)Copy SMILESCopy InChI

Affinity DataKi:  3.01E+3nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A receptor expressed in CHO-K1 cell membranes measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
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TargetKappa-type opioid receptor(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

LigandBDBM50579346(CHEMBL4867565)Copy SMILESCopy InChI

Affinity DataKi:  3.27E+3nMAssay Description:Binding affinity to human kappa opioid receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
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TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

LigandBDBM50579346(CHEMBL4867565)Copy SMILESCopy InChI

Affinity DataKi:  3.50E+3nMAssay Description:Binding affinity to human sigma 1 receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetD(2) dopamine receptor(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

LigandBDBM50579346(CHEMBL4867565)Copy SMILESCopy InChI

Affinity DataKi:  4.39E+3nMAssay Description:Displacement of [3H]-haloperidol from human D2L receptor expressed in HEK293 cell membranes measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

LigandBDBM50579346(CHEMBL4867565)Copy SMILESCopy InChI

Affinity DataKi:  4.61E+3nMAssay Description:Binding affinity to human adrenergic alpha2B receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

LigandBDBM50579346(CHEMBL4867565)Copy SMILESCopy InChI

Affinity DataIC50:  68nMAssay Description:Antagonist activity at human 5-HT3 receptor expressed in CHO-K1 cells assessed as inhibition of 5-HT induced inward currents preincubated for 30 sec ...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 2C19(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

LigandBDBM50579346(CHEMBL4867565)Copy SMILESCopy InChI

Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
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TargetCytochrome P450 1A2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

LigandBDBM50579346(CHEMBL4867565)Copy SMILESCopy InChI

Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
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TargetCytochrome P450 3A4(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

LigandBDBM50579346(CHEMBL4867565)Copy SMILESCopy InChI

Affinity DataIC50:  5.70E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI