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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
47
hits in this display
Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.280nM
Assay Description:
Displacement of [3H]MPEP from mGluR5 in rat brain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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Article
PubMed
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Target
Sigma non-opioid intracellular receptor 1
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to sigma 1 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
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Ligand Info
CHEMBL
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PC sid
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Article
PubMed
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Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to adrenergic beta2 receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
PubMed
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Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to 5HT1A receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
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Ligand Info
CHEMBL
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PC sid
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Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to 5HT1B receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to 5HT1D receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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Ligand Info
CHEMBL
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Article
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Target
5-hydroxytryptamine receptor 1E
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to 5HT1E receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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CHEMBL
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Article
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Target
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to 5HT2A receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to 5HT2B receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to 5HT2C receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to 5HT3 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 5A
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to 5HT5A receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to 5HT6 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 7
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to 5HT7 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-1A adrenergic receptor
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to adrenergic alpha1A receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-1B adrenergic receptor
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to adrenergic Alpha-1B receptor
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-1D adrenergic receptor
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to adrenergic Alpha-1D receptor
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-2A adrenergic receptor
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to adrenergic alpha2A receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-2C adrenergic receptor
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to adrenergic Alpha-2C receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to adrenergic beta1 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-3 adrenergic receptor
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to adrenergic beta3 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to dopamine D1 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to dopamine D2 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to dopamine D3 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(4) dopamine receptor
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to dopamine D4 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1B) dopamine receptor
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to dopamine D5 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to DAT
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kappa-type opioid receptor
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to KOR
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H1 receptor
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to histamine H1 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H2 receptor
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to histamine H2 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H3 receptor
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to histamine H3 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H4 receptor
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to histamine H4 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to muscarinic M1 receptor
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M2
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to muscarinic M2 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M3
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to muscarinic M3 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M4
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to muscarinic M4 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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Ligand Info
CHEMBL
PC cid
PC sid
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Article
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Target
Muscarinic acetylcholine receptor M5
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to muscarinic M5 receptor
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Metabotropic glutamate receptor 1
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to mGluR1 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to mGluR2 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
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Ligand Info
CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
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Target
Metabotropic glutamate receptor 4
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to mGluR4 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Metabotropic glutamate receptor 6
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to mGluR6 receptor
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
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Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Metabotropic glutamate receptor 8
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to mGluR8 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Mu-type opioid receptor
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to MOR
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
PubMed
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Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
Copy SMILES
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to NET
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to SERT receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Delta-type opioid receptor
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
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Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to DOR
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Alpha-2B adrenergic receptor
(Homo sapiens (Human))
National Institute Of Mental Health
Curated by
ChEMBL
Ligand
BDBM50336843
(3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonit...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity to adrenergic alpha2B receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI