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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
16
hits in this display
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by
ChEMBL
Ligand
BDBM50066788
((S)-3-(azetidin-2-ylmethoxy)-2-fluoropyridine | 3-...)
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Affinity Data
Ki: 0.0460nM
Assay Description:
Binding affinity for alpha4 beta-2 nAChR using [3H]epibatidine in rat brain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
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Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by
ChEMBL
Ligand
BDBM50066788
((S)-3-(azetidin-2-ylmethoxy)-2-fluoropyridine | 3-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.0480nM
Assay Description:
Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 in rat brain using [3H]-cytisine as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by
ChEMBL
Ligand
BDBM50066788
((S)-3-(azetidin-2-ylmethoxy)-2-fluoropyridine | 3-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.0610nM
Assay Description:
Ability of compound to compete with 50 pM of 5-[125I]iodo-A-85,380 for receptor binding sites in rat brain membranes at room temperature
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat))
National Institute On Drug Abuse
Curated by
ChEMBL
Ligand
BDBM50066788
((S)-3-(azetidin-2-ylmethoxy)-2-fluoropyridine | 3-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.30nM
Assay Description:
Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat brain homogenate by scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4
(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50066788
((S)-3-(azetidin-2-ylmethoxy)-2-fluoropyridine | 3-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.30nM
Assay Description:
Displacement of [3H]epibatidine from rat alpha4beta2 nicotinic receptor expressed in human HEK293 cells by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4
(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50263094
((S)-3-(azetidin-2-ylmethoxy)-2-[18F]fluoropyridine...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.33nM
Assay Description:
Displacement of [3H]epibatidine from rat alpha4beta2 nAChR expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-2
(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50066788
((S)-3-(azetidin-2-ylmethoxy)-2-fluoropyridine | 3-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.40nM
Assay Description:
Displacement of [3H]epibatidine from rat alpha2beta2 nicotinic receptor expressed in human HEK293 cells by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-2
(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50263094
((S)-3-(azetidin-2-ylmethoxy)-2-[18F]fluoropyridine...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.44nM
Assay Description:
Displacement of [3H]epibatidine from rat alpha2beta2 nAChR expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-3
(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50066788
((S)-3-(azetidin-2-ylmethoxy)-2-fluoropyridine | 3-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3nM
Assay Description:
Displacement of [3H]epibatidine from rat alpha3beta2 nicotinic receptor expressed in human HEK293 cells by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-3
(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50263094
((S)-3-(azetidin-2-ylmethoxy)-2-[18F]fluoropyridine...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.02nM
Assay Description:
Displacement of [3H]epibatidine from rat alpha3beta2 nAChR expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-2
(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50066788
((S)-3-(azetidin-2-ylmethoxy)-2-fluoropyridine | 3-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 180nM
Assay Description:
Displacement of [3H]epibatidine from rat alpha2beta4 nicotinic receptor expressed in human HEK293 cells by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-2
(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50263094
((S)-3-(azetidin-2-ylmethoxy)-2-[18F]fluoropyridine...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 181nM
Assay Description:
Displacement of [3H]epibatidine from rat alpha2beta4 nAChR expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4
(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50263094
((S)-3-(azetidin-2-ylmethoxy)-2-[18F]fluoropyridine...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 188nM
Assay Description:
Displacement of [3H]epibatidine from rat alpha4beta4 nAChR expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4
(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50066788
((S)-3-(azetidin-2-ylmethoxy)-2-fluoropyridine | 3-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 190nM
Assay Description:
Displacement of [3H]epibatidine from rat alpha4beta4 nicotinic receptor expressed in human HEK293 cells by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-3
(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50263094
((S)-3-(azetidin-2-ylmethoxy)-2-[18F]fluoropyridine...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.68E+3nM
Assay Description:
Displacement of [3H]epibatidine from rat alpha3beta4 nAChR expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-3
(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50066788
((S)-3-(azetidin-2-ylmethoxy)-2-fluoropyridine | 3-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.70E+3nM
Assay Description:
Displacement of [3H]epibatidine from rat alpha3beta4 nicotinic receptor expressed in human HEK293 cells by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI