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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
14
hits in this display
Target
Hrh3 protein
(RAT)
U. 109
Curated by
PDSP K
i
Database
Ligand
BDBM22916
(5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole |...)
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Affinity Data
Ki: 0.200nM
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Histamine H3 receptor
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM22916
(5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole |...)
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Affinity Data
Ki: 0.300nM
Assay Description:
Histamine H3 receptor affinity of compound was determined in rat cortical membranes using the H3 selective agonist ligand, [3H]N-alpha-methylhistamin...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Histamine H3 receptor
(Homo sapiens (Human))
Vrije Universiteit Amsterdam
Ligand
BDBM22916
(5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole |...)
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Copy InChI
Affinity Data
Ki: 0.630nM
Assay Description:
Ligand displacement assays were performed on The SK-N-MC/hH3R cell homogenates. Retained radioactivity was determined by liquid scintillation countin...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H3 receptor
(Homo sapiens (Human))
Vrije Universiteit Amsterdam
Ligand
BDBM22916
(5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.631nM
Assay Description:
Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Hrh3 protein
(RAT)
U. 109
Curated by
PDSP K
i
Database
Ligand
BDBM22916
(5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.900nM
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Histamine H3 receptor
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM22916
(5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1nM
Assay Description:
Binding affinity towards Histamine H3 receptor on synaptosomes from rat cerebral cortex
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H3 receptor
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM22916
(5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5nM
Assay Description:
In vitro antagonistic activity tested against Histamine H3 receptor on synaptosomes from rat cerebral cortex
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Hrh3 protein
(RAT)
U. 109
Curated by
PDSP K
i
Database
Ligand
BDBM22916
(5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5nM
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Histamine H3 receptor
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM22916
(5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5nM
Assay Description:
In vitro antagonistic activity tested against Histamine H3 receptor on synaptosomes from rat cerebral cortex
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H4 receptor
(Homo sapiens (Human))
Vu University Amsterdam
Curated by
ChEMBL
Ligand
BDBM22916
(5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 12.6nM
Assay Description:
Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H4 receptor
(Homo sapiens (Human))
Vu University Amsterdam
Curated by
ChEMBL
Ligand
BDBM22916
(5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 13nM
Assay Description:
Ligand displacement assays were performed on The SK-N-MC/hH4R cell homogenates. Retained radioactivity was determined by liquid scintillation countin...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H3 receptor
(Homo sapiens (Human))
Vrije Universiteit Amsterdam
Ligand
BDBM22916
(5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 41nM
Assay Description:
Inhibition of [125I]-iodoproxyfan binding to human histamine H3 receptor of CHO-K1 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H3 receptor
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM22916
(5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 71nM
Assay Description:
Inhibition of [125I]-iodoproxyfan from rat histamine H3 receptor expressed in CHO-K1 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H3 receptor
(GUINEA PIG)
De Novo Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM22916
(5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 5.01nM
Assay Description:
Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortex
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI