Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCoagulation factor XI(Homo sapiens (Human))
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM588063(US11541049, Example 5)
Affinity DataIC50:  0.160nMAssay Description:Reagents:Enzyme: human coagulation factor XIa; manufacturer: Haemtech;Substrate: Boc-Ile-Glu-Gly-Arg-AMC Acetate salt; manufacturer: Bachem;Reaction ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetCoagulation factor VII(Homo sapiens (Human))
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM588063(US11541049, Example 5)
Affinity DataIC50: >1.00E+4nMAssay Description:The test compounds were dissolved in assay buffer (50 mM Hepes, 150 mM NaCl, 5 mM CaCl2, pH 7.4) at a final concentration of 10 μM and 1 μM...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM588063(US11541049, Example 5)
Affinity DataIC50:  1.00E+4nMAssay Description:The test compounds were dissolved in assay buffer (50 mM Tris, 150 mM NaCl, 10 mM CaCl2, 0.05% Brij35, pH 7.5) at a final concentration of 10 μM...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent