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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetArginase-1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM290365((1S,2S)-1-amino-2-(3-boronopropyl)cyclopentanecarb...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human arginase1 in presence of DNTB by thio ornithine generation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM290365((1S,2S)-1-amino-2-(3-boronopropyl)cyclopentanecarb...)
Affinity DataIC50:  210nMAssay Description:Inhibition of human recombinant arginase 1 expressed in Escherichia coli BL21 (DE3) assessed as reduction in urea production using L-arginine as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM290365((1S,2S)-1-amino-2-(3-boronopropyl)cyclopentanecarb...)
Affinity DataIC50:  625nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290365((1S,2S)-1-amino-2-(3-boronopropyl)cyclopentanecarb...)
Affinity DataIC50:  625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM290365((1S,2S)-1-amino-2-(3-boronopropyl)cyclopentanecarb...)
Affinity DataIC50:  625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290365((1S,2S)-1-amino-2-(3-boronopropyl)cyclopentanecarb...)
Affinity DataIC50:  625nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM290365((1S,2S)-1-amino-2-(3-boronopropyl)cyclopentanecarb...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290365((1S,2S)-1-amino-2-(3-boronopropyl)cyclopentanecarb...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent