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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Arginase-1
(Homo sapiens (Human))
New England Discovery Partners
Curated by
ChEMBL
Ligand
BDBM290372
((3R,4S)-3-amino-4-(3-boronopropyl)pyrrolidine-3-ca...)
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Affinity Data
IC50: 110nM
Assay Description:
Inhibition of human recombinant arginase 1 expressed in Escherichia coli BL21 (DE3) assessed as reduction in urea production using L-arginine as subs...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Arginase-1
(Homo sapiens (Human))
New England Discovery Partners
Curated by
ChEMBL
Ligand
BDBM290372
((3R,4S)-3-amino-4-(3-boronopropyl)pyrrolidine-3-ca...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 113nM
Assay Description:
Inhibition of human arginase1 in presence of DNTB by thio ornithine generation assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Arginase-1
(Homo sapiens (Human))
New England Discovery Partners
Curated by
ChEMBL
Ligand
BDBM290372
((3R,4S)-3-amino-4-(3-boronopropyl)pyrrolidine-3-ca...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 625nM
Assay Description:
Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Arginase-2, mitochondrial
(Homo sapiens (Human))
Mars
US Patent
Ligand
BDBM290372
((3R,4S)-3-amino-4-(3-boronopropyl)pyrrolidine-3-ca...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 625nM
pH: 7.4 T: 2°C
Assay Description:
Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Arginase-1
(Homo sapiens (Human))
New England Discovery Partners
Curated by
ChEMBL
Ligand
BDBM290372
((3R,4S)-3-amino-4-(3-boronopropyl)pyrrolidine-3-ca...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 625nM
pH: 7.4 T: 2°C
Assay Description:
Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Arginase-2, mitochondrial
(Homo sapiens (Human))
Mars
US Patent
Ligand
BDBM290372
((3R,4S)-3-amino-4-(3-boronopropyl)pyrrolidine-3-ca...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 625nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Arginase-1
(Homo sapiens (Human))
New England Discovery Partners
Curated by
ChEMBL
Ligand
BDBM290372
((3R,4S)-3-amino-4-(3-boronopropyl)pyrrolidine-3-ca...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.00E+3nM
Assay Description:
Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Arginase-2, mitochondrial
(Homo sapiens (Human))
Mars
US Patent
Ligand
BDBM290372
((3R,4S)-3-amino-4-(3-boronopropyl)pyrrolidine-3-ca...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.00E+3nM
Assay Description:
Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI