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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Histone-lysine N-methyltransferase SMYD3
(Homo sapiens (Human))
Epizyme
US Patent
Ligand
BDBM432822
(N-((1R,3r,5S)-8-((4- aminocyclohexyl)sulfonyl)-8- ...)
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Affinity Data
IC50: 0.800nM
Assay Description:
The assays were all performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use....
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Histone-lysine N-methyltransferase SMYD3
(Homo sapiens (Human))
Epizyme
US Patent
Ligand
BDBM432836
(N-((1R,3R,5S)-8-(((1r,4R)-4- aminocyclohexyl)sulfo...)
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Affinity Data
IC50: 1.30nM
Assay Description:
The assays were all performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use....
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
In Depth
Details
US Patent
PDB
3D Structure (crystal)
Copy BDB DOI