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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
5-hydroxytryptamine receptor 3A/3B/3C/3D/3E
(Homo sapiens (Human))
Virginia Commonwealth University
Curated by
ChEMBL
Ligand
BDBM50053615
(3-Chloro-Phenyl biguanide | CHEMBL13790 | N-(3-chl...)
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Affinity Data
Ki: 17nM
Assay Description:
Compound was tested for the inhibition of [3H]-GR-65,630 binding to 5-hydroxytryptamine 3 receptor expressed in NG 108-15 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
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Article
PubMed
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Target
Integrin alpha-V/beta-3
(Homo sapiens (Human))
Chinese Academy Of Medical Sciences And Peking Union Medical College
Curated by
ChEMBL
Ligand
BDBM50053615
(3-Chloro-Phenyl biguanide | CHEMBL13790 | N-(3-chl...)
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Affinity Data
IC50: 1.91E+5nM
Assay Description:
Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiin
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50053615
(3-Chloro-Phenyl biguanide | CHEMBL13790 | N-(3-chl...)
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Affinity Data
EC50: 3.80E+3nM
Assay Description:
Agonist activity at human 5-HT43A receptor expressed in Xenopus laevis oocytes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
Patents
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In Depth
Details
Article
PubMed
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Target
Trace amine-associated receptor 5
(Mus musculus)
University Of Genoa
Curated by
ChEMBL
Ligand
BDBM50053615
(3-Chloro-Phenyl biguanide | CHEMBL13790 | N-(3-chl...)
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Affinity Data
EC50: >1.00E+4nM
Assay Description:
Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
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CHEMBL
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In Depth
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Article
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Target
5-hydroxytryptamine receptor 3A/3B
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50053615
(3-Chloro-Phenyl biguanide | CHEMBL13790 | N-(3-chl...)
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Affinity Data
EC50: 2.80E+3nM
Assay Description:
Agonist activity at human 5-HT43AB receptor expressed in Xenopus laevis oocytes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 3A
(Mus musculus (house mouse))
Virtua Drug
Curated by
ChEMBL
Ligand
BDBM50053615
(3-Chloro-Phenyl biguanide | CHEMBL13790 | N-(3-chl...)
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Affinity Data
EC50: 800nM
Assay Description:
Agonist activity at wild type mouse 5HT3A receptor expressed in Xenopus oocyte by two-electrode voltage patch clamp method
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI