Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL

LigandBDBM50133084((R)-N-{(S)-2-Cyclopropyl-1-[(S)-4-guanidino-1-(thi...)Copy SMILESCopy InChI

Affinity DataIC50:  820nMAssay Description:Inhibitory activity against tissue coagulation factor VII.More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetCoagulation factor X(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL

LigandBDBM50133084((R)-N-{(S)-2-Cyclopropyl-1-[(S)-4-guanidino-1-(thi...)Copy SMILESCopy InChI

Affinity DataIC50:  2.12E+3nMAssay Description:Inhibitory activity against coagulation factor X.More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProthrombin(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL

LigandBDBM50133084((R)-N-{(S)-2-Cyclopropyl-1-[(S)-4-guanidino-1-(thi...)Copy SMILESCopy InChI

Affinity DataIC50:  9.20E+3nMAssay Description:Inhibitory activity against thrombin (IIa).More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI