Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetProthrombin(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50133093((R)-N-{(S)-1-[(S)-4-guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against thrombin (IIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50133093((R)-N-{(S)-1-[(S)-4-guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50133093((R)-N-{(S)-1-[(S)-4-guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against tissue coagulation factor VII.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50133093((R)-N-{(S)-1-[(S)-4-guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50133093((R)-N-{(S)-1-[(S)-4-guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50:  240nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50133093((R)-N-{(S)-1-[(S)-4-guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50:  240nMAssay Description:Inhibitory activity against coagulation factor X.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed