Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCoagulation factor X(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL

LigandBDBM50133096((R)-N-{(S)-2-(3,5-Difluoro-phenyl)-1-[(S)-4-guanid...)Copy SMILESCopy InChI

Affinity DataIC50:  180nMAssay Description:Inhibitory activity against coagulation factor X.More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL

LigandBDBM50133096((R)-N-{(S)-2-(3,5-Difluoro-phenyl)-1-[(S)-4-guanid...)Copy SMILESCopy InChI

Affinity DataIC50:  190nMAssay Description:Inhibitory activity against tissue coagulation factor VII.More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProthrombin(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL

LigandBDBM50133096((R)-N-{(S)-2-(3,5-Difluoro-phenyl)-1-[(S)-4-guanid...)Copy SMILESCopy InChI

Affinity DataIC50:  6.82E+3nMAssay Description:Inhibitory activity against thrombin (IIa).More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI