Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM50094803(5-Guanidino-2-[3-(4-sulfamoyl-phenyl)-thioureido]-...)Copy SMILESCopy InChI

Affinity DataKi:  15nMAssay Description:Inhibitory activity against human recombinant carbonic anhydrase IIMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCarbonic anhydrase 4(Bos taurus (bovine))
Universit£

Curated by ChEMBL

LigandBDBM50094803(5-Guanidino-2-[3-(4-sulfamoyl-phenyl)-thioureido]-...)Copy SMILESCopy InChI

Affinity DataKi:  61nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV from lung microsomesMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM50094803(5-Guanidino-2-[3-(4-sulfamoyl-phenyl)-thioureido]-...)Copy SMILESCopy InChI

Affinity DataKi:  115nMAssay Description:Inhibitory activity against human recombinant carbonic anhydrase IMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI