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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
20
hits in this display
Target
Urokinase-type plasminogen activator
(Homo sapiens (Human))
Celera
Ligand
BDBM14150
(APC-11417 | CA-12 | CRA-11417 | {amino[6-fluoro-2-...)
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Affinity Data
Ki: 16nM
Assay Description:
Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Urokinase-type plasminogen activator
(Homo sapiens (Human))
Celera
Ligand
BDBM50106239
(6-Fluoro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
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Affinity Data
Ki: 20nM
Assay Description:
The compound was tested for inhibition of human urokinase type plasminogen activator (microPa)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Urokinase-type plasminogen activator
(Homo sapiens (Human))
Celera
Ligand
BDBM14150
(APC-11417 | CA-12 | CRA-11417 | {amino[6-fluoro-2-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 20nM ΔG°: -43.5kJ/mole
pH: 7.4 T: 2°C
Assay Description:
Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Urokinase-type plasminogen activator
(Homo sapiens (Human))
Celera
Ligand
BDBM14150
(APC-11417 | CA-12 | CRA-11417 | {amino[6-fluoro-2-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 20nM
Assay Description:
Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine protease 1
(Bos taurus (bovine))
Celera
Ligand
BDBM14150
(APC-11417 | CA-12 | CRA-11417 | {amino[6-fluoro-2-...)
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Affinity Data
Ki: 190nM
Assay Description:
Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tissue-type plasminogen activator
(Homo sapiens (Human))
Axys Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50106239
(6-Fluoro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
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Affinity Data
Ki: 350nM
Assay Description:
The compound was tested for inhibition of human plasmin
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Plasminogen
(Homo sapiens (Human))
Axys Pharmaceutical
Ligand
BDBM14150
(APC-11417 | CA-12 | CRA-11417 | {amino[6-fluoro-2-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 350nM
Assay Description:
Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine protease 1
(Homo sapiens (Human))
Celera
Ligand
BDBM14150
(APC-11417 | CA-12 | CRA-11417 | {amino[6-fluoro-2-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 660nM
Assay Description:
Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Coagulation factor VII
(Homo sapiens (Human))
Axys Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50106239
(6-Fluoro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 750nM
Assay Description:
The compound was tested for inhibition of human coagulation factor VII
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Coagulation factor X
(Homo sapiens (Human))
Celera
Ligand
BDBM14150
(APC-11417 | CA-12 | CRA-11417 | {amino[6-fluoro-2-...)
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Copy InChI
Affinity Data
Ki: 980nM
Assay Description:
Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine protease 1/Trypsin-2
(Homo sapiens (Human))
Axys Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50106239
(6-Fluoro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
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Copy InChI
Affinity Data
Ki: 1.10E+3nM
Assay Description:
The compound was tested for inhibition of human trypsin
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine protease 1
(Bos taurus (bovine))
Celera
Ligand
BDBM14150
(APC-11417 | CA-12 | CRA-11417 | {amino[6-fluoro-2-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.10E+3nM
Assay Description:
Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Coagulation factor X
(Homo sapiens (Human))
Celera
Ligand
BDBM14150
(APC-11417 | CA-12 | CRA-11417 | {amino[6-fluoro-2-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.30E+3nM
Assay Description:
Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Coagulation factor X
(Homo sapiens (Human))
Celera
Ligand
BDBM50106239
(6-Fluoro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.30E+3nM
Assay Description:
Binding affinity against human coagulation factor X
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Urokinase-type plasminogen activator [179-431,I214M,N322A,S371A]
(Homo sapiens (Human))
Celera
Ligand
BDBM14150
(APC-11417 | CA-12 | CRA-11417 | {amino[6-fluoro-2-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.60E+3nM
Assay Description:
Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tissue-type plasminogen activator
(Homo sapiens (Human))
Axys Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50106239
(6-Fluoro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.60E+3nM
Assay Description:
The compound was tested for inhibition of human tissue plasminogen activator
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tissue-type plasminogen activator
(Homo sapiens (Human))
Axys Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM14150
(APC-11417 | CA-12 | CRA-11417 | {amino[6-fluoro-2-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.60E+3nM
Assay Description:
Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prothrombin
(Homo sapiens (Human))
Celera
Ligand
BDBM14150
(APC-11417 | CA-12 | CRA-11417 | {amino[6-fluoro-2-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.30E+3nM
Assay Description:
Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prothrombin
(Homo sapiens (Human))
Celera
Ligand
BDBM14150
(APC-11417 | CA-12 | CRA-11417 | {amino[6-fluoro-2-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 7.50E+3nM
Assay Description:
Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prothrombin
(Homo sapiens (Human))
Celera
Ligand
BDBM50106239
(6-Fluoro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 7.50E+3nM
Assay Description:
The compound was tested for inhibition of human thrombin
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI