Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetProthrombin(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL

LigandBDBM50272577((S)-1-((R)-Pyrrolidine-2-carbonyl)-pyrrolidine-2-c...)Copy SMILESCopy InChI

Affinity DataIC50:  88nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCoagulation factor VII(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL

LigandBDBM50272577((S)-1-((R)-Pyrrolidine-2-carbonyl)-pyrrolidine-2-c...)Copy SMILESCopy InChI

Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human factor 7a-tissue factor complexMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI