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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetProthrombin(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14594(N-[(4-carbamimidoylphenyl)methyl]-2-{2,6-difluoro-...)
Affinity DataIC50:  1.56E+3nMpH: 8.0 T: 2°CAssay Description:Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14594(N-[(4-carbamimidoylphenyl)methyl]-2-{2,6-difluoro-...)
Affinity DataIC50:  1.64E+4nMpH: 8.0 T: 2°CAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14594(N-[(4-carbamimidoylphenyl)methyl]-2-{2,6-difluoro-...)
Affinity DataIC50: >3.00E+4nMpH: 8.0 T: 2°CAssay Description:Human Factor Xa and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed