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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Prothrombin
(Homo sapiens (Human))
Pharmacia
Curated by
ChEMBL
Ligand
BDBM14498
(CHEMBL75084 | N-[(4-carbamimidoylphenyl)methyl]-2-...)
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Affinity Data
IC50: 150nM
Assay Description:
Inhibitory activity of the compound against Thrombin
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Prothrombin
(Homo sapiens (Human))
Pharmacia
Curated by
ChEMBL
Ligand
BDBM14498
(CHEMBL75084 | N-[(4-carbamimidoylphenyl)methyl]-2-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 160nM
Assay Description:
Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prothrombin
(Homo sapiens (Human))
Pharmacia
Curated by
ChEMBL
Ligand
BDBM14498
(CHEMBL75084 | N-[(4-carbamimidoylphenyl)methyl]-2-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 160nM
Assay Description:
Inhibition of human thrombin using H-D-phenylalanyl-L-pipecolyl-L-arginine-p-nitroaniline dihydrochloride as substrate after 60 mins
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine protease 1
(Homo sapiens (Human))
Pharmacia
Curated by
ChEMBL
Ligand
BDBM14498
(CHEMBL75084 | N-[(4-carbamimidoylphenyl)methyl]-2-...)
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Affinity Data
IC50: 240nM
Assay Description:
Inhibitory activity of the compound against trypsin
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Coagulation factor VII/Tissue factor
(Homo sapiens (Human))
Hefei University Of Technology
Curated by
ChEMBL
Ligand
BDBM14498
(CHEMBL75084 | N-[(4-carbamimidoylphenyl)methyl]-2-...)
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Affinity Data
IC50: 630nM
Assay Description:
Inhibition of recombinant soluble tissue factor (unknown origin)/recombinant human factor 7a using N-methylsulfonyl-D-phe-gly arg-p-nitroaniline as s...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Coagulation factor VII
(Homo sapiens (Human))
Pharmacia
Ligand
BDBM14498
(CHEMBL75084 | N-[(4-carbamimidoylphenyl)methyl]-2-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 630nM
pH: 8.0 T: 2°C
Assay Description:
Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI