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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14510(2-[3-(benzylamino)-5-chloro-2-oxo-6-phenyl-1,2-dih...)
Affinity DataIC50:  770nMpH: 8.0 T: 2°CAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Hefei University Of Technology

Curated by ChEMBL
LigandPNGBDBM14510(2-[3-(benzylamino)-5-chloro-2-oxo-6-phenyl-1,2-dih...)
Affinity DataIC50:  770nMAssay Description:Inhibition of recombinant soluble tissue factor (unknown origin)/recombinant human factor 7a using N-methylsulfonyl-D-phe-gly arg-p-nitroaniline as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Hefei University Of Technology

Curated by ChEMBL
LigandPNGBDBM14510(2-[3-(benzylamino)-5-chloro-2-oxo-6-phenyl-1,2-dih...)
Affinity DataIC50:  7.63E+3nMAssay Description:Inhibition of human thrombin using H-D-phenylalanyl-L-pipecolyl-L-arginine-p-nitroaniline dihydrochloride as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Hefei University Of Technology

Curated by ChEMBL
LigandPNGBDBM14510(2-[3-(benzylamino)-5-chloro-2-oxo-6-phenyl-1,2-dih...)
Affinity DataIC50:  7.63E+3nMAssay Description:Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed