Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

LigandBDBM14524(2-[3-(benzylsulfanyl)-5-chloro-2-oxo-6-phenyl-1,2-...)Copy SMILESCopy InChI

Affinity DataIC50:  6.40E+3nMAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProthrombin(Homo sapiens (Human))
Pharmacia

LigandBDBM14524(2-[3-(benzylsulfanyl)-5-chloro-2-oxo-6-phenyl-1,2-...)Copy SMILESCopy InChI

Affinity DataIC50:  8.00E+3nMAssay Description:Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI