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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
Serine/threonine-protein kinase Nek2
(Homo sapiens (Human))
Newcastle University
Curated by
ChEMBL
Ligand
BDBM50553207
(CHEMBL4786783)
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Affinity Data
IC50: 18nM
Assay Description:
Inhibition of human NEK2 by kinase-profiling analysis
More data for this Ligand-Target Pair
Target Info
PDB
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antibodypedia
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Target
Serine/threonine-protein kinase Nek2
(Homo sapiens (Human))
Newcastle University
Curated by
ChEMBL
Ligand
BDBM50553207
(CHEMBL4786783)
Copy SMILES
Copy InChI
Affinity Data
IC50: 62nM
Assay Description:
Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...
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Target Info
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antibodypedia
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Target
Aurora kinase A
(Homo sapiens (Human))
Newcastle University
Curated by
ChEMBL
Ligand
BDBM50553207
(CHEMBL4786783)
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Affinity Data
IC50: 80nM
Assay Description:
Inhibition of Aurora A (unknown origin) preincubated with enzyme for 15 mins followed by substrate/ATP challenge for 90 mins by ProfilerPro plate bas...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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Target
NUAK family SNF1-like kinase 1
(Homo sapiens (Human))
Newcastle University
Curated by
ChEMBL
Ligand
BDBM50553207
(CHEMBL4786783)
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Affinity Data
IC50: 120nM
Assay Description:
Inhibition of human NAUK1 by kinase-profiling analysis
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Target Info
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Target
Tyrosine-protein kinase JAK2
(Homo sapiens (Human))
Newcastle University
Curated by
ChEMBL
Ligand
BDBM50553207
(CHEMBL4786783)
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Affinity Data
IC50: 220nM
Assay Description:
Inhibition of human JAK2 by kinase-profiling analysis
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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Target
Mitogen-activated protein kinase kinase kinase 7
(Homo sapiens (Human))
Newcastle University
Curated by
ChEMBL
Ligand
BDBM50553207
(CHEMBL4786783)
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Affinity Data
IC50: 240nM
Assay Description:
Inhibition of human TAK1 by kinase-profiling analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
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Target
Mitogen-activated protein kinase kinase kinase 9
(Homo sapiens (Human))
Newcastle University
Curated by
ChEMBL
Ligand
BDBM50553207
(CHEMBL4786783)
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Affinity Data
IC50: 270nM
Assay Description:
Inhibition of human MLK1 by kinase-profiling analysis
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
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B.MOAD
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antibodypedia
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In Depth
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Target
Mitogen-activated protein kinase kinase kinase 11
(Homo sapiens (Human))
Newcastle University
Curated by
ChEMBL
Ligand
BDBM50553207
(CHEMBL4786783)
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Affinity Data
IC50: 320nM
Assay Description:
Inhibition of human MLK3 by kinase-profiling analysis
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Target Info
PDB
NCI pathway
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KEGG
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Target
Dual specificity mitogen-activated protein kinase kinase 1
(Homo sapiens (Human))
Newcastle University
Curated by
ChEMBL
Ligand
BDBM50553207
(CHEMBL4786783)
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Affinity Data
IC50: 550nM
Assay Description:
Inhibition of human MKK1 by kinase-profiling analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human))
Newcastle University
Curated by
ChEMBL
Ligand
BDBM50553207
(CHEMBL4786783)
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Affinity Data
IC50: 560nM
Assay Description:
Inhibition of human ChK1 by kinase-profiling analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
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Target
Serine/threonine-protein kinase TBK1
(Homo sapiens (Human))
Newcastle University
Curated by
ChEMBL
Ligand
BDBM50553207
(CHEMBL4786783)
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Affinity Data
IC50: 740nM
Assay Description:
Inhibition of human TBK1 by kinase-profiling analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
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In Depth
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Article
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Target
Cytoplasmic tyrosine-protein kinase BMX
(Homo sapiens (Human))
Newcastle University
Curated by
ChEMBL
Ligand
BDBM50553207
(CHEMBL4786783)
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Affinity Data
IC50: 830nM
Assay Description:
Inhibition of BMX (unknown origin) preincubated with enzyme for 15 mins followed by substrate/ATP challenge for 90 mins by ProfilerPro plate based la...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI