Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL

LigandBDBM50257487(CHEMBL4090462)Copy SMILESCopy InChI

Affinity DataIC50:  560nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged GRK2 expressed in baculovirus expression system using ulight topo2alpha as substrate preincubat...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL

LigandBDBM50257487(CHEMBL4090462)Copy SMILESCopy InChI

Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ROCK2 catalytic domain (1 to 553 residues) expressed in baculovirus expression system using STK...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI