Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL

LigandBDBM50134961(CHEMBL3746142)Copy SMILESCopy InChI

Affinity DataIC50:  81nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL

LigandBDBM50134961(CHEMBL3746142)Copy SMILESCopy InChI

Affinity DataIC50:  500nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI