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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
C-C chemokine receptor type 6
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50463578
(CHEMBL4250007)
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Affinity Data
IC50: 13nM
Assay Description:
Inhibition of human CCR6 expressed in CHO cells assessed as decrease in CCL20-induced reduction of forskolin-stimulated cAMP accumulation preincubate...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
C-C chemokine receptor type 6
(Macaca mulatta)
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50463578
(CHEMBL4250007)
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Affinity Data
IC50: 16nM
Assay Description:
Inhibition of monkey CCR6 expressed in CHO cells assessed as decrease in CCL20-induced reduction of forskolin-stimulated cAMP accumulation preincubat...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
C-C chemokine receptor type 6
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50463578
(CHEMBL4250007)
Copy SMILES
Copy InChI
Affinity Data
IC50: 41nM
Assay Description:
Inhibition of human CCR6 expressed in CHO cells assessed as decrease in human CCL20-dependent cell migration incubated for 4 hrs by Diff-Quik stainin...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
C-C chemokine receptor type 7
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50463578
(CHEMBL4250007)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of human CCR7 expressed in CHO cells assessed as decrease in CCL19-induced reduction of forskolin-stimulated cAMP accumulation preincubate...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
C-C chemokine receptor type 1
(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50463578
(CHEMBL4250007)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of human CCR1 expressed in CHO cells assessed as decrease in RANTES-induced reduction of forskolin-stimulated cAMP accumulation preincubat...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI