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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat))
Merck Frosst Centre For Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50312688
(5-(4-(2-(trifluoromethyl)phenoxy)piperidin-1-yl)-1...)
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Affinity Data
IC50: 3nM
Assay Description:
Inhibition of SCD1 in Wistar rat liver microsome assessed as [3H]stearoyl-CoA to [3H]oleoyl-CoA conversion pretreated 1 hr before [3H]stearoyl-CoA ad...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Stearoyl-CoA desaturase
(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50312688
(5-(4-(2-(trifluoromethyl)phenoxy)piperidin-1-yl)-1...)
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Copy InChI
Affinity Data
IC50: 7nM
Assay Description:
Inhibition of SCD1 in human HepG2 cells assessed as [14C]stearic acid to [14C]oleic acid conversion pretreated 15 mins before [14C]stearic acid addit...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI