Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 6 hits in this display
BDBM214807(US9296734, 22 | US9296734, 8)
BDBM214807(US9296734, 22 | US9296734, 8)
IC50: 21nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
BDBM214807(US9296734, 22 | US9296734, 8)
BDBM214807(US9296734, 22 | US9296734, 8)
IC50: 203nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
BDBM214807(US9296734, 22 | US9296734, 8)
BDBM214807(US9296734, 22 | US9296734, 8)
IC50: >4.00E+5nMpH: 3.5Assay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair