Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL

LigandBDBM50300718(8-(benzo[d][1,3]dioxol-5-yl)-8-(3-(2-fluoropyridin...)Copy SMILESCopy InChI

Affinity DataIC50:  160nMAssay Description:Inhibition of human BACE1 by FRETMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-secretase 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL

LigandBDBM50300718(8-(benzo[d][1,3]dioxol-5-yl)-8-(3-(2-fluoropyridin...)Copy SMILESCopy InChI

Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of human BACE2 by FRETMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCathepsin D(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL

LigandBDBM50300718(8-(benzo[d][1,3]dioxol-5-yl)-8-(3-(2-fluoropyridin...)Copy SMILESCopy InChI

Affinity DataIC50:  1.54E+4nMAssay Description:Inhibition of human cathepsin D by FRETMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI