Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAminopeptidase N(Homo sapiens (Human))
Merck Sharpe And Dohme

Curated by ChEMBL

LigandBDBM50336494(6-amino-5,6,8,9-tetrahydrobenzocycloheptene-7-one,...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human aminopeptidase N by Dixon plot analysisMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
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TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Merck Sharpe And Dohme

Curated by ChEMBL

LigandBDBM50336494(6-amino-5,6,8,9-tetrahydrobenzocycloheptene-7-one,...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of aminopeptidase activity of human leukotriene A4 hydrolase by Dixon plot analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
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TargetCytosol aminopeptidase(Bos taurus (bovine))
Merck Sharpe And Dohme

Curated by ChEMBL

LigandBDBM50336494(6-amino-5,6,8,9-tetrahydrobenzocycloheptene-7-one,...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of bovine lens cytosolic leucine aminopeptidase by Dixon plot analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI