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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetProline-rich AKT1 substrate 1(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM386008(2-[4-(6,7-Dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)...)
Affinity DataIC50:  750nMAssay Description:A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose response cu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM386008(2-[4-(6,7-Dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)...)
Affinity DataIC50:  750nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent