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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT)
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50042998
(5-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-d...)
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Affinity Data
Ki: 150nM
Assay Description:
Displacement of [3H]clonidine from adrenergic alpha 2 receptor of rat cerebral cortical membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Beta-1 adrenergic receptor
(Rattus norvegicus (Rat))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50042998
(5-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-d...)
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Affinity Data
Ki: 1.50E+3nM
Assay Description:
Displacement of [3H]dihydroalprenolol from adrenergic beta 1 receptor of rat cerebral cortical membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50042998
(5-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-d...)
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Affinity Data
Ki: 2.30E+3nM
Assay Description:
Displacement of [3H]WB-4101 from adrenergic alpha 1 receptor of rat cerebral cortical membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Beta-2 adrenergic receptor
(Rattus norvegicus)
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM50042998
(5-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-d...)
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Affinity Data
Ki: 5.50E+3nM
Assay Description:
Binding affinity against adrenergic beta 2 receptor versus 1 nM [3H]dihydroalprenolol in rat cerebral cerebellar membranes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Beta-1/Beta-2/Beta-3 adrenergic receptor
(Rattus norvegicus (Rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50042998
(5-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-d...)
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Affinity Data
EC50: 4.00E+3nM
Assay Description:
Displacement of [3H]dihydroalprenolol from beta-adrenergic receptor in Sprague-Dawley rat cerebral cortical membrane
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Alpha-1A adrenergic receptor/Alpha-1B adrenergic receptor/Alpha-1D adrenergic receptor/Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50042998
(5-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-d...)
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Copy InChI
Affinity Data
EC50: 5.00E+3nM
Assay Description:
Agonist activity at alpha-adrenergic receptor in Sprague-Dawley rat cerebral cortex assessed as [3H]cAMP accumulation by liquid scintillation spectro...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1/Beta-2/Beta-3 adrenergic receptor
(Rattus norvegicus (Rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50042998
(5-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-d...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.00E+3nM
Assay Description:
Agonist activity at beta-adrenergic receptor in Sprague-Dawley rat cerebral cortex assessed as [3H]cAMP accumulation by liquid scintillation spectros...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-1A adrenergic receptor/Alpha-1B adrenergic receptor/Alpha-1D adrenergic receptor/Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50042998
(5-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-d...)
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Copy InChI
Affinity Data
EC50: 1.50E+4nM
Assay Description:
Displacement of [3H]WB4101 from alpha-adrenergic receptor in Sprague-Dawley rat cerebral cortical membrane
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI