Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 10 hits in this display   

TargetNitric oxide synthase, brain(Homo sapiens (Human))
Northwestern University

US Patent

LigandBDBM344412(US9783500, Compound 7)Copy SMILESCopy InChI

Affinity DataKi:  25nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails US PatentPDB3D Structure (crystal)
Copy BDB DOI

TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

US Patent

LigandBDBM344412(US9783500, Compound 7)Copy SMILESCopy InChI

Affinity DataKi:  25nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails US PatentPDB3D Structure (crystal)
Copy BDB DOI

TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

US Patent

LigandBDBM344412(US9783500, Compound 7)Copy SMILESCopy InChI

Affinity DataKi:  82nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails US PatentPDB3D Structure (crystal)
Copy BDB DOI

TargetNitric oxide synthase, brain(Homo sapiens (Human))
Northwestern University

US Patent

LigandBDBM344412(US9783500, Compound 7)Copy SMILESCopy InChI

Affinity DataKi:  135nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails US PatentPDB3D Structure (crystal)
Copy BDB DOI

TargetNitric oxide synthase, brain(Homo sapiens (Human))
Northwestern University

US Patent

LigandBDBM344412(US9783500, Compound 7)Copy SMILESCopy InChI

Affinity DataKi:  135nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails US PatentPDB3D Structure (crystal)
Copy BDB DOI

TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

US Patent

LigandBDBM344412(US9783500, Compound 7)Copy SMILESCopy InChI

Affinity DataKi:  160nMAssay Description:Inhibition of wild type recombinant rat nNOS expressed in Escherichia coli assessed as nitric oxide production by hemoglobin capture assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Northwestern University

US Patent

LigandBDBM344412(US9783500, Compound 7)Copy SMILESCopy InChI

Affinity DataKi:  4.83E+3nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails US Patent
Copy BDB DOI

TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL

LigandBDBM344412(US9783500, Compound 7)Copy SMILESCopy InChI

Affinity DataKi:  1.29E+4nMAssay Description:Inhibition of recombinant bovine eNOS expressed in Escherichia coli assessed as nitric oxide production by hemoglobin capture assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetNitric oxide synthase, brain(Mus musculus)
Northwestern University

US Patent

LigandBDBM344412(US9783500, Compound 7)Copy SMILESCopy InChI

Affinity DataKi:  3.27E+4nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails US PatentPDB3D Structure (crystal)
Copy BDB DOI

TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL

LigandBDBM344412(US9783500, Compound 7)Copy SMILESCopy InChI

Affinity DataKi:  3.36E+4nMAssay Description:Inhibition of recombinant murine iNOS expressed in Escherichia coli assessed as nitric oxide production by hemoglobin capture assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails ArticlePubMed
Copy BDB DOI