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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
15
hits in this display
Target
Carbonic anhydrase 14
(Homo sapiens (Human))
Istanbul University
Ligand
BDBM25916
(3-(4-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
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Affinity Data
Ki: 7nM
Assay Description:
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
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Article
PubMed
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Target
Alpha-carbonic anhydrase domain-containing protein
(Caenorhabditis elegans)
Istanbul University
Ligand
BDBM25916
(3-(4-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
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Affinity Data
Ki: 11.5nM ΔG°: -45.3kJ/mole
pH: 7.4 T: 2°C
Assay Description:
An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...
More data for this Ligand-Target Pair
Target Info
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KEGG
UniProtKB/TrEMBL
GoogleScholar
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Article
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Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Istanbul University
Ligand
BDBM25916
(3-(4-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
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Affinity Data
Ki: 40.8nM ΔG°: -42.2kJ/mole
pH: 7.4 T: 2°C
Assay Description:
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Carbonic anhydrase 15 [19-324]
(Mus musculus (mouse))
Istanbul University
Ligand
BDBM25916
(3-(4-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
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Affinity Data
Ki: 47nM
Assay Description:
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Carbonic anhydrase 7
(Homo sapiens (Human))
Istanbul University
Ligand
BDBM25916
(3-(4-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
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Affinity Data
Ki: 58nM
Assay Description:
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 12
(Homo sapiens (Human))
Istanbul University
Ligand
BDBM25916
(3-(4-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
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Affinity Data
Ki: 60nM
Assay Description:
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 9
(Homo sapiens (Human))
Istanbul University
Ligand
BDBM25916
(3-(4-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
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Affinity Data
Ki: 63nM
Assay Description:
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Carbonic anhydrase
(Candida albicans (Yeast))
Istanbul University
Curated by
ChEMBL
Ligand
BDBM25916
(3-(4-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
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Affinity Data
Ki: 94nM
Assay Description:
inhibition of Candida albicans recombinant Nce103 after 15 mins by stopped-flow CO2 hydration assay
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
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GoogleScholar
Ligand Info
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PC sid
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In Depth
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Article
PubMed
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Target
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human))
Istanbul University
Ligand
BDBM25916
(3-(4-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
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Affinity Data
Ki: 619nM
Assay Description:
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 1
(Homo sapiens (Human))
Istanbul University
Ligand
BDBM25916
(3-(4-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
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Affinity Data
Ki: 659nM ΔG°: -35.3kJ/mole
pH: 7.4 T: 2°C
Assay Description:
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 5B, mitochondrial
(Homo sapiens (Human))
Istanbul University
Ligand
BDBM25916
(3-(4-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
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Affinity Data
Ki: 672nM
Assay Description:
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 13
(Mus musculus (mouse))
Istanbul University
Ligand
BDBM25916
(3-(4-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
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Copy InChI
Affinity Data
Ki: 759nM
Assay Description:
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 4
(Homo sapiens (Human))
Istanbul University
Ligand
BDBM25916
(3-(4-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
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Affinity Data
Ki: 2.91E+3nM
Assay Description:
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 6
(Homo sapiens (Human))
Istanbul University
Ligand
BDBM25916
(3-(4-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
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Affinity Data
Ki: 4.45E+3nM
Assay Description:
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 3
(Homo sapiens (Human))
Istanbul University
Ligand
BDBM25916
(3-(4-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
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Affinity Data
Ki: 5.20E+6nM
Assay Description:
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI