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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 15 hits in this display   

TargetAlpha-carbonic anhydrase domain-containing protein(Caenorhabditis elegans)
Istanbul University

LigandPNGBDBM25910(3-(4-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole...)
Affinity DataKi:  6nM ΔG°:  -46.9kJ/molepH: 7.4 T: 2°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25910(3-(4-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole...)
Affinity DataKi:  7.80nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25910(3-(4-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole...)
Affinity DataKi:  15.5nM ΔG°:  -44.6kJ/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 15 [19-324](Mus musculus (mouse))
Istanbul University

LigandPNGBDBM25910(3-(4-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole...)
Affinity DataKi:  49nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25910(3-(4-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole...)
Affinity DataKi:  54nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25910(3-(4-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole...)
Affinity DataKi:  58nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Candida albicans (Yeast))
Istanbul University

Curated by ChEMBL
LigandPNGBDBM25910(3-(4-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole...)
Affinity DataKi:  61nMAssay Description:inhibition of Candida albicans recombinant Nce103 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25910(3-(4-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole...)
Affinity DataKi:  65nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25910(3-(4-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole...)
Affinity DataKi:  108nM ΔG°:  -39.8kJ/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25910(3-(4-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole...)
Affinity DataKi:  576nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25910(3-(4-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole...)
Affinity DataKi:  705nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 13(Mus musculus (mouse))
Istanbul University

LigandPNGBDBM25910(3-(4-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole...)
Affinity DataKi:  740nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25910(3-(4-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole...)
Affinity DataKi:  3.65E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25910(3-(4-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole...)
Affinity DataKi:  3.98E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 3(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25910(3-(4-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole...)
Affinity DataKi:  7.50E+6nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed