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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 11 hits in this display   

TargetCarbonic anhydrase 12(Homo sapiens (Human))
King Saud University

Curated by ChEMBL
LigandPNGBDBM152638(4-(1,3-Dioxoisoindolin-2-yl)benzenesulphonamide (1...)
Affinity DataKi:  0.530nMAssay Description:Inhibition of human carbonic anhydrase 12 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
King Saud University

Curated by ChEMBL
LigandPNGBDBM152638(4-(1,3-Dioxoisoindolin-2-yl)benzenesulphonamide (1...)
Affinity DataKi:  2.20nMAssay Description:Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
King Saud University

Curated by ChEMBL
LigandPNGBDBM152638(4-(1,3-Dioxoisoindolin-2-yl)benzenesulphonamide (1...)
Affinity DataKi:  3.80nMAssay Description:Inhibition of human carbonic anhydrase 9 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
King Saud University

Curated by ChEMBL
LigandPNGBDBM152638(4-(1,3-Dioxoisoindolin-2-yl)benzenesulphonamide (1...)
Affinity DataKi:  29nMAssay Description:Inhibition of human carbonic anhydrase 1 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
King Saud University

Curated by ChEMBL
LigandPNGBDBM152638(4-(1,3-Dioxoisoindolin-2-yl)benzenesulphonamide (1...)
Affinity DataKi:  42nMAssay Description:Inhibition of human carbonic anhydrase II (CAII)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM152638(4-(1,3-Dioxoisoindolin-2-yl)benzenesulphonamide (1...)
Affinity DataKi:  79nMAssay Description:Inhibition of bovine carbonic anhydrase IV (CAIV)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
King Saud University

Curated by ChEMBL
LigandPNGBDBM152638(4-(1,3-Dioxoisoindolin-2-yl)benzenesulphonamide (1...)
Affinity DataKi:  1.04E+3nMAssay Description:Inhibition of human carbonic anhydrase I (CAI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM152638(4-(1,3-Dioxoisoindolin-2-yl)benzenesulphonamide (1...)
Affinity DataKi:  1.60E+4nMAssay Description:Binding affinity to Nav 1.2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
King Saud University

Curated by ChEMBL
LigandPNGBDBM152638(4-(1,3-Dioxoisoindolin-2-yl)benzenesulphonamide (1...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of ovine COX2-mediated prostaglandin alpha production by enzyme immuno assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2 (Virus))
Birla Institute of Technology

LigandPNGBDBM152638(4-(1,3-Dioxoisoindolin-2-yl)benzenesulphonamide (1...)
Affinity DataIC50: >1.00E+5nMpH: 8.5Assay Description:To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
King Saud University

Curated by ChEMBL
LigandPNGBDBM152638(4-(1,3-Dioxoisoindolin-2-yl)benzenesulphonamide (1...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ovine COX1-mediated prostaglandin alpha production by enzyme immuno assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed