Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM50079037(6-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylcarbamoyl)-py...)Copy SMILESCopy InChI

Affinity DataKi:  6nMAssay Description:Inhibitory activity against human recombinant carbonic anhydrase IIMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCarbonic anhydrase 4(Bos taurus (bovine))
Universit£

Curated by ChEMBL

LigandBDBM50079037(6-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylcarbamoyl)-py...)Copy SMILESCopy InChI

Affinity DataKi:  21nMAssay Description:Inhibitory activity against bovine lung microsomes carbonic anhydrase isozyme IV (bCA IV).More data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM50079037(6-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylcarbamoyl)-py...)Copy SMILESCopy InChI

Affinity DataKi:  36nMAssay Description:Inhibitory activity against human cloned carbonic anhydrase isozyme I (hCA I, cytosolic form).More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI