Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 36 hits in this display   

TargetHistone deacetylase 1(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  9nMAssay Description:The following non-trypsin coupled in-vitro HDAC enzymatic endpoint assay was used to assay the compounds of the invention. Below is a standardized pr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  22nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  49nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University Of East Anglia

Curated by ChEMBL
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  100nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  100nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  100nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  110nMAssay Description:Inhibition of recombinant human C-terminal His-tagged HDAC2 expressed in baculovirus expression system using Ac-peptide as substrate incubated for 60...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  112nMAssay Description:Inhibition of recombinant human full length HDAC1 expressed in baculovirus infected Sf9 insect cells using biotinylated lysine 9 acetylated histone H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  130nMAssay Description:Inhibition of recombinant full length human HDAC1 (1 to 482 residues) expressed in baculovirus expression system using Ac-Leu-Gly-Lys(Ac)-AMC as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  140nMAssay Description:HDACs assay was performed according to standard Protocols (Fluorgenic HDACs 1, 2, and 3 assay kit, BPS Bioscience™). All of the compounds, with Chida...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase(Homo sapiens (Human))
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  167nMAssay Description:Inhibition of HDAC (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  167nMAssay Description:Inhibition of recombinant full-length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using Fluor-de-Lys as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  196nMAssay Description:Inhibition of HDAC1 (unknown origin) using p53 (379 to 382 residues) (RHKK(Ac-AMC) as fluorogenic substrate incubated for 1 hrs by fluorescence based...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  196nMAssay Description:Inhibition of HDAC1 (unknown origin) using RHKK(Ac)AMC fluorogenic peptide as substrate preincubated for 10 mins followed by substrate addition for 1...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  196nMAssay Description:Inhibition of human HDAC1 using RHKKAc fluorogenic peptide as substrate preincubated for 10 mins followed by substrate addition by fluorescence based...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  200nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  220nMAssay Description:HDACs assay was performed according to standard Protocols (Fluorgenic HDACs 1, 2, and 3 assay kit, BPS Bioscience™). All of the compounds, with Chida...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University Of East Anglia

Curated by ChEMBL
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  235nMAssay Description:Inhibition of HDAC10 (unknown origin) using Fluor de Lys substrate by fluorescence assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  263nMAssay Description:HDACs assay was performed according to standard Protocols (Fluorgenic HDACs 1, 2, and 3 assay kit, BPS Bioscience™). All of the compounds, with Chida...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  265nMAssay Description:Inhibition of HDAC3 (unknown origin) using Fluor de Lys substrate by fluorescence assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  296nMAssay Description:Inhibition of HDAC1 (unknown origin) using Fluor de Lys substrate by fluorescence assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  330nMAssay Description:Inhibition of human recombinant C-terminal His-tagged HDAC3/NCOR2 (395 to 489 residus) using Ac-peptide as substrate incubated for 60 mins by fluorom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  400nMAssay Description:HDACs assay was performed according to standard Protocols (Fluorgenic HDACs 1, 2, and 3 assay kit, BPS Bioscience™). All of the compounds, with Chida...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 11(Homo sapiens (Human))
University Of East Anglia

Curated by ChEMBL
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  400nMAssay Description:Inhibition of HDAC11 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  450nMAssay Description:Inhibition of HDAC2 (unknown origin) using Fluor de Lys substrate by fluorescence assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  620nMAssay Description:HDACs assay was performed according to standard Protocols (Fluorgenic HDACs 1, 2, and 3 assay kit, BPS Bioscience™). All of the compounds, with Chida...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  690nMAssay Description:HDACs assay was performed according to standard Protocols (Fluorgenic HDACs 1, 2, and 3 assay kit, BPS Bioscience™). All of the compounds, with Chida...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of East Anglia

Curated by ChEMBL
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  700nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
University Of East Anglia

Curated by ChEMBL
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  760nMAssay Description:Inhibition of HDAC11 (unknown origin) using Fluor de Lys substrate by fluorescence assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of East Anglia

Curated by ChEMBL
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  833nMAssay Description:Inhibition of HDAC8 (unknown origin) using Fluor de Lys substrate by fluorescence assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human NAMPT using NAM and PRPP as substrates incubated for 90 mins in presence of NMNAT by fluorometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of East Anglia

Curated by ChEMBL
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
University Of East Anglia

Curated by ChEMBL
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
University Of East Anglia

Curated by ChEMBL
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of East Anglia

Curated by ChEMBL
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of East Anglia

Curated by ChEMBL
LigandPNGBDBM50457079(CS-055 | CS055 | Chidamide | Epidaza in China | HB...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed