Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 14 hits in this display   

TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50530003(CHEMBL4552057)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of recombinant full length HDAC1 (unknown origin) using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50530003(CHEMBL4552057)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of recombinant full length HDAC1 (unknown origin) using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50530003(CHEMBL4552057)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of recombinant full length N-terminal FLAG-tagged human HDAC10 expressed in baculovirus infected sf9 cells using Ac-peptide-AMC as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50530003(CHEMBL4552057)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of recombinant full length N-terminal FLAG-tagged human HDAC10 expressed in baculovirus infected sf9 cells using Ac-peptide-AMC as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50530003(CHEMBL4552057)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of recombinant full length human HDAC2 expressed in baculovirus expression system using Ac-peptide-AMC as substrate preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50530003(CHEMBL4552057)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of recombinant full length human HDAC2 expressed in baculovirus expression system using Ac-peptide-AMC as substrate preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50530003(CHEMBL4552057)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of recombinant full length HDAC6 (unknown origin) using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50530003(CHEMBL4552057)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of recombinant full length HDAC6 (unknown origin) using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50530003(CHEMBL4552057)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of recombinant full length HDAC3 (unknown origin) using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50530003(CHEMBL4552057)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of recombinant full length HDAC3 (unknown origin) using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50530003(CHEMBL4552057)
Affinity DataIC50:  36nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged human HDAC8 expressed in baculovirus expression system using Ac-peptide-AMC as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50530003(CHEMBL4552057)
Affinity DataIC50:  36nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged human HDAC8 expressed in baculovirus expression system using Ac-peptide-AMC as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50530003(CHEMBL4552057)
Affinity DataIC50:  40nMAssay Description:Inhibition of recombinant N-terminal FLAG-tagged human mTOR (1362 to end residues) using ULight-4E-BP1 (Thr37/46) peptide as substrate after 1 hr by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50530003(CHEMBL4552057)
Affinity DataIC50:  40nMAssay Description:Inhibition of recombinant N-terminal FLAG-tagged human mTOR (1362 to end residues) using ULight-4E-BP1 (Thr37/46) peptide as substrate after 1 hr by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed