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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Histone deacetylase 1
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM50229189
(CHEMBL253868 | US9096559, 2a | [4-(4-amino-bipheny...)
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Affinity Data
IC50: 10nM
Assay Description:
Novel compounds were tested for their ability to inhibit histone deacetylase, subtype 1 (HDAC1) using an in vitro deacetylation assay. The enzyme sou...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
US Patent
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Target
Histone deacetylase 1
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM50229189
(CHEMBL253868 | US9096559, 2a | [4-(4-amino-bipheny...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of HDAC1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 2
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50229189
(CHEMBL253868 | US9096559, 2a | [4-(4-amino-bipheny...)
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Affinity Data
IC50: 72nM
Assay Description:
Inhibition of HDAC2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50229189
(CHEMBL253868 | US9096559, 2a | [4-(4-amino-bipheny...)
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Affinity Data
IC50: 3.00E+3nM
Assay Description:
Displacement of [35S]MK-499 from ERG expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Histone deacetylase 3
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50229189
(CHEMBL253868 | US9096559, 2a | [4-(4-amino-bipheny...)
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Affinity Data
IC50: 6.18E+3nM
Assay Description:
Inhibition of HDAC3
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 8
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50229189
(CHEMBL253868 | US9096559, 2a | [4-(4-amino-bipheny...)
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Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of HDAC8
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 7
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50229189
(CHEMBL253868 | US9096559, 2a | [4-(4-amino-bipheny...)
Copy SMILES
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Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of HDAC7
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 6
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50229189
(CHEMBL253868 | US9096559, 2a | [4-(4-amino-bipheny...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of HDAC6
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 5
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50229189
(CHEMBL253868 | US9096559, 2a | [4-(4-amino-bipheny...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of HDAC5
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI